Ontology highlight
ABSTRACT:
SUBMITTER: Ligr M
PROVIDER: S-EPMC3192795 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
Ligr Martin M Patwa Ruzeen Rohintan RR Daniels Garrett G Pan Lorraine L Wu Xinyu X Li Yirong Y Tian Liantian L Wang Zhenxing Z Xu Ruliang R Wu Jingjing J Chen Fan F Liu Jinsong J Wei Jian-Jun JJ Lee Peng P
PloS one 20111013 10
Hormones, including estrogen and progesterone, and their receptors play an important role in the development and progression of ovarian carcinoma. Androgen, its receptor and coactivators have also been implicated in these processes. p44/Mep50/WDR77 was identified as a subunit of the methylosome complex and lately characterized as a steroid receptor coactivator that enhances androgen receptor as well as estrogen receptor-mediated transcriptional activity in a ligand-dependent manner. We previousl ...[more]