Ontology highlight
ABSTRACT:
SUBMITTER: Peng Y
PROVIDER: S-EPMC3822728 | biostudies-literature | 2010 Dec
REPOSITORIES: biostudies-literature
Peng Yi Y Li Yirong Y Gellert Lan Lin LL Zou Xuanyi X Wang Jun J Singh Baljit B Xu Ruliang R Chiriboga Luis L Daniels Garrett G Pan Ruimin R Zhang David Y DY Garabedian Michael J MJ Schneider Robert J RJ Wang Zhengxin Z Lee Peng P
Journal of cellular and molecular medicine 20101201 12
Hormones and their receptors play an important role in the development and progression of breast carcinoma. Although the primary focus has been on oestrogen and oestrogen receptor (ER), androgen, androgen receptor (AR) and its coactivator(s) have been implicated in tumorigenesis of breast carcinoma and warrant further investigation. AR coactivator p44/Mep50 is identified as a subunit of methylosome complex and lately characterized as an AR coactivator that enhances AR mediated transcription acti ...[more]