Ontology highlight
ABSTRACT:
SUBMITTER: Lee HJ
PROVIDER: S-EPMC3195623 | biostudies-literature | 2011 Oct
REPOSITORIES: biostudies-literature
Lee Ho Jun HJ Lairson Luke L LL Rich Jamie R JR Lameignere Emilie E Wakarchuk Warren W WW Withers Stephen G SG Strynadka Natalie C J NCJ
The Journal of biological chemistry 20110805 41
Sialic acids play important roles in various biological processes and typically terminate the oligosaccharide chains on the cell surfaces of a wide range of organisms, including mammals and bacteria. Their attachment is catalyzed by a set of sialyltransferases with defined specificities both for their acceptor sugars and the position of attachment. However, little is known of how this specificity is encoded. The structure of the bifunctional sialyltransferase Cst-II of the human pathogen Campylo ...[more]