Ontology highlight
ABSTRACT:
SUBMITTER: Ghosh S
PROVIDER: S-EPMC3200501 | biostudies-literature | 2011 Nov
REPOSITORIES: biostudies-literature
Ghosh Sudakshina S Erzurum Serpil C SC
Biochimica et biophysica acta 20110621 11
<h4>Background</h4>Asthma, a chronic inflammatory disease is typically characterized by bronchoconstriction and airway hyper-reactivity.<h4>Scope of review</h4>A wealth of studies applying chemistry, molecular and cell biology to animal model systems and human asthma over the last decade has revealed that asthma is associated with increased synthesis of the gaseous molecule nitric oxide (NO).<h4>Major conclusion</h4>The high NO levels in the oxidative environment of the asthmatic airway lead to ...[more]