Ontology highlight
ABSTRACT:
SUBMITTER: Mestdagh P
PROVIDER: S-EPMC3203610 | biostudies-literature | 2011 Nov
REPOSITORIES: biostudies-literature
Nucleic acids research 20110810 20
While a growing body of evidence implicates regulatory miRNA modules in various aspects of human disease and development, insights into specific miRNA function remain limited. Here, we present an innovative approach to elucidate tissue-specific miRNA functions that goes beyond miRNA target prediction and expression correlation. This approach is based on a multi-level integration of corresponding miRNA and mRNA gene expression levels, miRNA target prediction, transcription factor target predictio ...[more]