Ontology highlight
ABSTRACT:
SUBMITTER: Neupane M
PROVIDER: S-EPMC3205445 | biostudies-literature | 2011 Dec
REPOSITORIES: biostudies-literature
Neupane Mahesh M Abu-Ali Galeb S GS Mitra Avishek A Lacher David W DW Manning Shannon D SD Riordan James T JT
Microbial pathogenesis 20110816 6
Variation in disease severity among Escherichia coli O157:H7 infections may result from differential expression of Shiga toxin 2 (Stx2). Eleven strains belonging to four prominent phylogenetic clades, including clade 8 strains representative of the 2006 U.S. spinach outbreak, were examined for stx2 expression by real-time PCR and western blot analysis. Clade 8 strains were shown to overexpress stx2 basally, and following induction with ciprofloxacin when compared to strains from clades 1-3. Diff ...[more]