Ontology highlight
ABSTRACT:
SUBMITTER: Park JY
PROVIDER: S-EPMC3205825 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
Park Jong-Yi JY Park Mi-Ryung MR Kwon Deug-Nam DN Kang Min-Hui MH Oh Mihye M Han Jae-Woong JW Cho Ssang-Goo SG Park Chankyu C Kim Dong-Ku DK Song Hyuk H Oh Jae-Wook JW Kim Jin-Hoi JH
Journal of biomedicine & biotechnology 20111025
We examined whether deficiency of the GGTA1 gene in pigs altered the expression of several glycosyltransferase genes. Real-time RT-PCR and glycosyltransferase activity showed that 2 sialyltransferases [α2,3-sialyltransferase (α2,3ST) and α2,6-sialyltransferase (α2,6ST)] in the heterozygote GalT KO liver have higher expression levels and activities compared to controls. Enzyme-linked lectin assays indicated that there were also more sialic acid-containing glycoconjugate epitopes in GalT KO livers ...[more]