Ontology highlight
ABSTRACT:
SUBMITTER: Pan L
PROVIDER: S-EPMC3206604 | biostudies-literature | 2011 Oct
REPOSITORIES: biostudies-literature
Pan Li L Matthew Susan S Lantvit Daniel D DD Zhang Xiaoli X Ninh Tran Ngoc TN Chai Heebyung H Carcache de Blanco Esperanza J EJ Soejarto Djaja D DD Swanson Steven M SM Kinghorn A Douglas AD
Journal of natural products 20111005 10
Bioassay-guided fractionation was conducted on a chloroform-soluble extract of the aerial parts of Piper sarmentosum collected in Vietnam, monitored by a mitochondrial transmembrane potential assay using HT-29 human colon cancer cells. This led to the isolation of four new C-benzylated dihydroflavones, sarmentosumins A-D (1-4), as well as 14 known compounds. The structures of the new compounds were elucidated on the basis of spectroscopic data interpretation. Among these compounds, 1-4 as well a ...[more]