Ontology highlight
ABSTRACT:
SUBMITTER: Nguyen J
PROVIDER: S-EPMC3210348 | biostudies-literature | 2011 Nov
REPOSITORIES: biostudies-literature
Nguyen John J Nishimura Nozomi N Fetcho Robert N RN Iadecola Costantino C Schaffer Chris B CB
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20110629 11
The accumulation of small strokes has been linked to cognitive dysfunction. Although most animal models have focused on the impact of arteriole occlusions, clinical evidence indicates that venule occlusions may also be important. We used two-photon excited fluorescence microscopy to quantify changes in blood flow and vessel diameter in capillaries after occlusion of single ascending or surface cortical venules as a function of the connectivity between the measured capillary and the occluded venu ...[more]