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Class 1 integron containing metallo-beta-lactamase gene blaVIM-2 in Pseudomonas aeruginosa clinical strains isolated in Japan.

ABSTRACT: Four bla(VIM-2) gene-harboring Pseudomonas aeruginosa strains were identified. These strains possessed a class 1 integron harboring ORF1, bla(VIM-2), and aacA4 gene cassettes. The transposon-mediated horizontal spread of the bla(VIM-2) gene among these strains was suggested, which increases the threat that the bla(VIM-2) gene will disseminate among diverse genera of bacteria.

SUBMITTER: Yatsuyanagi J

PROVIDER: S-EPMC321541 | biostudies-literature | 2004 Feb

REPOSITORIES: biostudies-literature

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Class 1 integron containing metallo-beta-lactamase gene blaVIM-2 in Pseudomonas aeruginosa clinical strains isolated in Japan.

Yatsuyanagi Jun J Saito Shioko S Harata Seizaburo S Suzuki Noriyuki N Ito Yuko Y Amano Ken-Ichi K Enomoto Katsuhiko K

Antimicrobial agents and chemotherapy 20040201 2

Four bla(VIM-2) gene-harboring Pseudomonas aeruginosa strains were identified. These strains possessed a class 1 integron harboring ORF1, bla(VIM-2), and aacA4 gene cassettes. The transposon-mediated horizontal spread of the bla(VIM-2) gene among these strains was suggested, which increases the threat that the bla(VIM-2) gene will disseminate among diverse genera of bacteria. ...[more]

PMID: 14742222

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