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Two novel class I integron arrays containing IMP-18 metallo-?-lactamase gene in Pseudomonas aeruginosa clinical isolates from Puerto Rico.

ABSTRACT: During a ?-lactam resistance surveillance study, 12 IMP-18-positive Pseudomonas aeruginosa isolates belonging to 9 different pulsed-field gel electrophoresis groups were identified. In nine isolates, a class I integron with a novel gene array was identified that contained bla(IMP-18) and bla(OXA-224), while in two isolates the class I integron contained bla(IMP-18) and bla(OXA-2) but in a new arrangement. Our findings show the dissemination of two novel class I integrons in P. aeruginosa from different regions of Puerto Rico.

SUBMITTER: Martinez T

PROVIDER: S-EPMC3318352 | biostudies-literature | 2012 Apr

REPOSITORIES: biostudies-literature

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Two novel class I integron arrays containing IMP-18 metallo-β-lactamase gene in Pseudomonas aeruginosa clinical isolates from Puerto Rico.

Martínez T T Vazquez G J GJ Aquino E E EE Goering R V RV Robledo I E IE

Antimicrobial agents and chemotherapy 20120130 4

During a β-lactam resistance surveillance study, 12 IMP-18-positive Pseudomonas aeruginosa isolates belonging to 9 different pulsed-field gel electrophoresis groups were identified. In nine isolates, a class I integron with a novel gene array was identified that contained bla(IMP-18) and bla(OXA-224), while in two isolates the class I integron contained bla(IMP-18) and bla(OXA-2) but in a new arrangement. Our findings show the dissemination of two novel class I integrons in P. aeruginosa from di ...[more]

PMID: 22290962

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