Ontology highlight
ABSTRACT:
SUBMITTER: Azuaje FJ
PROVIDER: S-EPMC3216539 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
Azuaje Francisco J FJ Zhang Lu L Devaux Yvan Y Wagner Daniel R DR
Scientific reports 20110802
The systems-level characterization of drug-target associations in myocardial infarction (MI) has not been reported to date. We report a computational approach that combines different sources of drug and protein interaction information to assemble the myocardial infarction drug-target interactome network (My-DTome). My-DTome comprises approved and other drugs interlinked in a single, highly-connected network with modular organization. We show that approved and other drugs may both be highly conne ...[more]