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General mechanism of actomyosin contractility.


ABSTRACT: Stress generation by myosin minifilaments is analyzed via simulation of their motion in a random actin network. The stresses are overwhelmingly contractile because minifilament equilibrium positions having contractile stress have lower energy than those for expansive stress. Force chains lead to unexpectedly large stresses.

SUBMITTER: Dasanayake NL 

PROVIDER: S-EPMC3226764 | biostudies-literature | 2011 Sep

REPOSITORIES: biostudies-literature

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General mechanism of actomyosin contractility.

Dasanayake Nilushi L NL   Michalski Paul J PJ   Carlsson Anders E AE  

Physical review letters 20110908 11


Stress generation by myosin minifilaments is analyzed via simulation of their motion in a random actin network. The stresses are overwhelmingly contractile because minifilament equilibrium positions having contractile stress have lower energy than those for expansive stress. Force chains lead to unexpectedly large stresses. ...[more]

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