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In vivo evidence that retinal bipolar cells generate spikes modulated by light.


ABSTRACT: Retinal bipolar cells have been assumed to generate purely graded responses to light. To test this idea we imaged the presynaptic calcium transient in live zebrafish. We found that ON, OFF, transient and sustained bipolar cells are all capable of generating fast 'all-or-none' calcium transients modulated by visual stimulation.

SUBMITTER: Dreosti E 

PROVIDER: S-EPMC3232443 | biostudies-literature | 2011 Jun

REPOSITORIES: biostudies-literature

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In vivo evidence that retinal bipolar cells generate spikes modulated by light.

Dreosti Elena E   Esposti Federico F   Baden Tom T   Lagnado Leon L  

Nature neuroscience 20110626 8


Retinal bipolar cells have been assumed to generate purely graded responses to light. To test this idea we imaged the presynaptic calcium transient in live zebrafish. We found that ON, OFF, transient and sustained bipolar cells are all capable of generating fast 'all-or-none' calcium transients modulated by visual stimulation. ...[more]

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