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Whole-genome sequences of two Borrelia afzelii and two Borrelia garinii Lyme disease agent isolates.

ABSTRACT: Human Lyme disease is commonly caused by several species of spirochetes in the Borrelia genus. In Eurasia these species are largely Borrelia afzelii, B. garinii, B. burgdorferi, and B. bavariensis sp. nov. Whole-genome sequencing is an excellent tool for investigating and understanding the influence of bacterial diversity on the pathogenesis and etiology of Lyme disease. We report here the whole-genome sequences of four isolates from two of the Borrelia species that cause human Lyme disease, B. afzelii isolates ACA-1 and PKo and B. garinii isolates PBr and Far04.

SUBMITTER: Casjens SR

PROVIDER: S-EPMC3232841 | biostudies-literature | 2011 Dec

REPOSITORIES: biostudies-literature

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Whole-genome sequences of two Borrelia afzelii and two Borrelia garinii Lyme disease agent isolates.

Casjens Sherwood R SR Mongodin Emmanuel F EF Qiu Wei-Gang WG Dunn John J JJ Luft Benjamin J BJ Fraser-Liggett Claire M CM Schutzer Steve E SE

Journal of bacteriology 20111201 24

Human Lyme disease is commonly caused by several species of spirochetes in the Borrelia genus. In Eurasia these species are largely Borrelia afzelii, B. garinii, B. burgdorferi, and B. bavariensis sp. nov. Whole-genome sequencing is an excellent tool for investigating and understanding the influence of bacterial diversity on the pathogenesis and etiology of Lyme disease. We report here the whole-genome sequences of four isolates from two of the Borrelia species that cause human Lyme disease, B. ...[more]

PMID: 22123755

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