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Carboxylases in natural and synthetic microbial pathways.

ABSTRACT: Carboxylases are among the most important enzymes in the biosphere, because they catalyze a key reaction in the global carbon cycle: the fixation of inorganic carbon (CO?). This minireview discusses the physiological roles of carboxylases in different microbial pathways that range from autotrophy, carbon assimilation, and anaplerosis to biosynthetic and redox-balancing functions. In addition, the current and possible future uses of carboxylation reactions in synthetic biology are discussed. Such uses include the possible transformation of the greenhouse gas carbon dioxide into value-added compounds and the production of novel antibiotics.

SUBMITTER: Erb TJ

PROVIDER: S-EPMC3233076 | biostudies-literature | 2011 Dec

REPOSITORIES: biostudies-literature

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Carboxylases in natural and synthetic microbial pathways.

Erb Tobias J TJ

Applied and environmental microbiology 20111014 24

Carboxylases are among the most important enzymes in the biosphere, because they catalyze a key reaction in the global carbon cycle: the fixation of inorganic carbon (CO₂). This minireview discusses the physiological roles of carboxylases in different microbial pathways that range from autotrophy, carbon assimilation, and anaplerosis to biosynthetic and redox-balancing functions. In addition, the current and possible future uses of carboxylation reactions in synthetic biology are discussed. Such ...[more]

PMID: 22003013

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Carboxylases in natural and synthetic microbial pathways.

Publications

Carboxylases in natural and synthetic microbial pathways.

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