Ontology highlight
ABSTRACT:
SUBMITTER: Piggott BJ
PROVIDER: S-EPMC3233480 | biostudies-literature | 2011 Nov
REPOSITORIES: biostudies-literature
Piggott Beverly J BJ Liu Jie J Feng Zhaoyang Z Wescott Seth A SA Xu X Z Shawn XZ
Cell 20111101 4
C. elegans is widely used to dissect how neural circuits and genes generate behavior. During locomotion, worms initiate backward movement to change locomotion direction spontaneously or in response to sensory cues; however, the underlying neural circuits are not well defined. We applied a multidisciplinary approach to map neural circuits in freely behaving worms by integrating functional imaging, optogenetic interrogation, genetic manipulation, laser ablation, and electrophysiology. We found tha ...[more]