Ontology highlight
ABSTRACT:
SUBMITTER: Zhou C
PROVIDER: S-EPMC3237388 | biostudies-literature | 2011 Nov
REPOSITORIES: biostudies-literature
Zhou Chuankai C Slaughter Brian D BD Unruh Jay R JR Eldakak Amr A Rubinstein Boris B Li Rong R
Cell 20111101 5
During yeast cell division, aggregates of damaged proteins are segregated asymmetrically between the bud and the mother. It is thought that protein aggregates are cleared from the bud via actin cable-based retrograde transport toward the mother and that Bni1p formin regulates this transport. Here, we examined the dynamics of Hsp104-associated protein aggregates by video microscopy, particle tracking, and image correlation analysis. We show that protein aggregates undergo random walk without dire ...[more]