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Enantioselective conjugate allylation of cyclic enones.

ABSTRACT: Enantioselective organocatalytic 1,2-allylation of a cyclic enone followed by anionic oxy-Cope rearrangement delivered the ketone as a mixture of diastereomers. This appears to be a general method for the net enantioselective conjugate allylation of cyclic enones.

SUBMITTER: Taber DF

PROVIDER: S-EPMC3237403 | biostudies-literature | 2011 Sep

REPOSITORIES: biostudies-literature

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Enantioselective conjugate allylation of cyclic enones.

Taber Douglass F DF Gerstenhaber David A DA Berry James F JF

The Journal of organic chemistry 20110823 18

Enantioselective organocatalytic 1,2-allylation of a cyclic enone followed by anionic oxy-Cope rearrangement delivered the ketone as a mixture of diastereomers. This appears to be a general method for the net enantioselective conjugate allylation of cyclic enones. ...[more]

PMID: 21830779

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