Ontology highlight
ABSTRACT:
SUBMITTER: Lee B
PROVIDER: S-EPMC3239167 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
Scientific reports 20110920
Molecular crowding is a critical feature distinguishing intracellular environments from idealized solution-based environments and is essential to understanding numerous biochemical reactions, from protein folding to signal transduction. Many biochemical reactions are dramatically altered by crowding, yet it is extremely difficult to predict how crowding will quantitatively affect any particular reaction systems. We previously developed a novel stochastic off-lattice model to efficiently simulate ...[more]