Ontology highlight
ABSTRACT:
SUBMITTER: Morello LG
PROVIDER: S-EPMC3241699 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
Morello Luis G LG Coltri Patricia P PP Quaresma Alexandre J C AJ Simabuco Fernando M FM Silva Tereza C L TC Singh Guramrit G Nickerson Jeffrey A JA Oliveira Carla C CC Moore Melissa J MJ Zanchin Nilson I T NI
PloS one 20111216 12
NIP7 is one of the many trans-acting factors required for eukaryotic ribosome biogenesis, which interacts with nascent pre-ribosomal particles and dissociates as they complete maturation and are exported to the cytoplasm. By using conditional knockdown, we have shown previously that yeast Nip7p is required primarily for 60S subunit synthesis while human NIP7 is involved in the biogenesis of 40S subunit. This raised the possibility that human NIP7 interacts with a different set of proteins as com ...[more]