Ontology highlight
ABSTRACT:
SUBMITTER: Connolly SA
PROVIDER: S-EPMC3242325 | biostudies-literature | 2011 May
REPOSITORIES: biostudies-literature
Connolly Sarah A SA Jackson Julia O JO Jardetzky Theodore S TS Longnecker Richard R
Nature reviews. Microbiology 20110411 5
Herpesviruses are double-stranded DNA, enveloped viruses that infect host cells through fusion with either the host cell plasma membrane or endocytic vesicle membranes. Efficient infection of host cells by herpesviruses is remarkably more complex than infection by other viruses, as it requires the concerted effort of multiple glycoproteins and involves multiple host receptors. The structures of the major viral glycoproteins and a number of host receptors involved in the entry of the prototypical ...[more]