Ontology highlight
ABSTRACT:
SUBMITTER: Curocichin G
PROVIDER: S-EPMC3245328 | biostudies-literature | 2011 Dec
REPOSITORIES: biostudies-literature
Curocichin Ghenadie G Wu Ying Y McDade Thomas W TW Kuzawa Christopher W CW Borja Judith B JB Qin Li L Lange Ethan M EM Adair Linda S LS Lange Leslie A LA Mohlke Karen L KL
Journal of human genetics 20110922 12
C-reactive protein (CRP) is a component of nonspecific immune defense and is a reliable marker of low-grade inflammation involved in obesity, type 2 diabetes and cardiovascular disease. Genome-wide association studies in middle-aged and elderly populations, predominantly of European descent, demonstrated associations of CRP levels with single-nucleotide polymorphisms (SNPs) at several loci. To examine whether the variants identified are replicated in Filipino young adults, we applied Tobit regre ...[more]