Ontology highlight
ABSTRACT:
SUBMITTER: Glauser DL
PROVIDER: S-EPMC3253813 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Glauser Daniel L DL Kratz Anne-Sophie AS Stevenson Philip G PG
PloS one 20120109 1
Herpesvirus entry is a complicated process involving multiple virion glycoproteins and culminating in membrane fusion. Glycoprotein conformation changes are likely to play key roles. Studies of recombinant glycoproteins have revealed some structural features of the virion fusion machinery. However, how the virion glycoproteins change during infection remains unclear. Here using conformation-specific monoclonal antibodies we show in situ that each component of the Murid Herpesvirus-4 (MuHV-4) ent ...[more]