Ontology highlight
ABSTRACT:
SUBMITTER: Aguilar HC
PROVIDER: S-EPMC5270710 | biostudies-literature | 2016 Sep
REPOSITORIES: biostudies-literature
Current clinical microbiology reports 20160705 3
The family <i>Paramyxoviridae</i> includes many viruses that significantly affect human and animal health. An essential step in the paramyxovirus life cycle is viral entry into host cells, mediated by virus-cell membrane fusion. Upon viral entry, infection results in expression of the paramyxoviral glycoproteins on the infected cell surface. This can lead to cell-cell fusion (syncytia formation), often linked to pathogenesis. Thus membrane fusion is essential for both viral entry and cell-cell f ...[more]