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N-(4,6-Dimeth-oxy-pyrimidin-2-yl)-2-(3-methyl-phen-yl)acetamide.

ABSTRACT: In the title compound, C(15)H(17)N(3)O(3), the dihedral angle between the pyrimidine and benzene rings is 87.0?(7)°. In the crystal, mol-ecules are linked into inversion dimers with R(2) (2)(8) graph-set motifs by a pair of N-H?O hydrogen bonds. Weak C-H?O hydrogen bonds and inter-molecular ?-? inter-actions [centroid-centroid distance = 3.544?(1)?Å] are also observed.

SUBMITTER: Praveen AS

PROVIDER: S-EPMC3254559 | biostudies-literature | 2012 Jan

REPOSITORIES: biostudies-literature

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N-(4,6-Dimeth-oxy-pyrimidin-2-yl)-2-(3-methyl-phen-yl)acetamide.

Praveen A S AS Jasinski Jerry P JP Golen James A JA Yathirajan H S HS Narayana B B

Acta crystallographica. Section E, Structure reports online 20111223 Pt 1

In the title compound, C(15)H(17)N(3)O(3), the dihedral angle between the pyrimidine and benzene rings is 87.0 (7)°. In the crystal, mol-ecules are linked into inversion dimers with R(2) (2)(8) graph-set motifs by a pair of N-H⋯O hydrogen bonds. Weak C-H⋯O hydrogen bonds and inter-molecular π-π inter-actions [centroid-centroid distance = 3.544 (1) Å] are also observed. ...[more]

PMID: 22259508

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Methyl 2-{N-[2-(2,4-dichloro-phen-oxy)acet-yl]-4-[(4,6-dimeth-oxy-pyrimidin-2-yl)-oxy]anilino}propano-ate.

Project description:In the title mol-ecule, C(24)H(23)Cl(2)N(3)O(7), the central benzene ring forms dihedral angles of 65.71?(1) and 44.42?(1)° with the pyrimidine ring and the terminal benzene ring, respectively. In the crystal, molecules are linked via C-H?O hydrogen bonds.

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4,6-Dimeth-oxy-2-(methyl-sulfon-yl)pyrimidine.

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Methyl 2,6-bis-[(5-chloro-4,6-dimeth-oxy-pyrimidin-2-yl)-oxy]benzoate.

Project description:In the title compound, C(20)H(18)Cl(2)N(4)O(8), the two pyrimidine rings are inclined at dihedral angles of 66.68?(5) and 71.91?(6)° with respect to the central benzene ring. In the crystal structure, inter-molecular C-H?N hydrogen bonds link neighbouring mol-ecules into a ribbon-like structure along the b axis. The ribbons are inter-connected into a two-dimensional network parallel to the bc plane by short inter-molecular Cl?Cl [3.4427?(6)?Å] and Cl?O [3.1420?(9) and 3.1750?(11)?Å] inter-actions. The crystal structure is further stabilized by inter-molecular ?-? inter-actions [centroid-centroid distance 3.4552?(8)?Å] involving the pyrimidine rings.

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