Ontology highlight
ABSTRACT:
SUBMITTER: Song JL
PROVIDER: S-EPMC3254792 | biostudies-literature | 2012 Feb
REPOSITORIES: biostudies-literature
Song Jia L JL Stoeckius Marlon M Maaskola Jonas J Friedländer Marc M Stepicheva Nadezda N Juliano Celina C Lebedeva Svetlana S Thompson William W Rajewsky Nikolaus N Wessel Gary M GM
Developmental biology 20111203 1
microRNAs (miRNAs) are small noncoding RNAs that mediate post-transcriptional gene regulation and have emerged as essential regulators of many developmental events. The transcriptional network during early embryogenesis of the purple sea urchin, Strongylocentrotus purpuratus, is well described and can serve as an excellent model to test functional contributions of miRNAs in embryogenesis. We examined the loss of function phenotypes of major components of the miRNA biogenesis pathway. Inhibition ...[more]