Ontology highlight
ABSTRACT:
SUBMITTER: Boutte CC
PROVIDER: S-EPMC3256613 | biostudies-literature | 2012 Jan
REPOSITORIES: biostudies-literature
Boutte Cara C CC Henry Jonathan T JT Crosson Sean S
Journal of bacteriology 20111021 1
Caulobacter crescentus differentiates from a motile, foraging swarmer cell into a sessile, replication-competent stalked cell during its cell cycle. This developmental transition is inhibited by nutrient deprivation to favor the motile swarmer state. We identify two cell cycle regulatory signals, ppGpp and polyphosphate (polyP), that inhibit the swarmer-to-stalked transition in both complex and glucose-exhausted media, thereby increasing the proportion of swarmer cells in mixed culture. Upon dep ...[more]