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Morning hypertension in treated hypertensives: baseline characteristics and clinical implications.


ABSTRACT:

Background and objectives

Morning hypertension is closely related to target organ damage and cardiovascular events. Little data is available concerning the baseline characteristics and comprehensive blood pressure analysis of hypertensive patients on treatment with morning hypertension.

Subjects and methods

We evaluated 1,087 hypertensive patients who had taken stable anti-hypertensive medication at least 6 months. The enrolled patients measured their home blood pressure for 7 days. Baseline characteristics and the laboratory data were analyzed. Morning hypertension was defined as a morning blood pressure ?135/85 mm Hg and systolic or diastolic blood pressure difference between morning and evening exceeding 10 mm Hg.

Results

One hundred seventy three patients with morning hypertension showed a preponderance of males, older patients, alcohol consumers, and greater waist circumference and waist-to-hip ratio despite the same body mass index. Impaired fasting glucose and metabolic syndrome were more prevalent in the patients with morning hypertension. The morning hypertensives took more anti-hypertensive drugs and displayed higher blood pressure in the clinic and at home.

Conclusion

The worse clinical variables and relatively poorly controlled blood pressure of those with morning hypertension supports a potential relationship of morning hypertension with poor cardiovascular outcome. Morning blood pressure should be monitored at home for the optimal treatment of hypertension.

SUBMITTER: Lee JH 

PROVIDER: S-EPMC3257457 | biostudies-literature | 2011 Dec

REPOSITORIES: biostudies-literature

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Publications

Morning hypertension in treated hypertensives: baseline characteristics and clinical implications.

Lee Ju-Hee JH   Bae Jang-Whan JW   Park Jung Bae JB   Park Chang Gyu CG   Youn Ho-Joong HJ   Choi Dong Ju DJ   Ahn Young Keun YK   Shin Joon-Han JH   Rim Se-Joong SJ   Bae Jang-Ho JH   Kim Dong-Woon DW  

Korean circulation journal 20111231 12


<h4>Background and objectives</h4>Morning hypertension is closely related to target organ damage and cardiovascular events. Little data is available concerning the baseline characteristics and comprehensive blood pressure analysis of hypertensive patients on treatment with morning hypertension.<h4>Subjects and methods</h4>We evaluated 1,087 hypertensive patients who had taken stable anti-hypertensive medication at least 6 months. The enrolled patients measured their home blood pressure for 7 day  ...[more]

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