Ontology highlight
ABSTRACT:
SUBMITTER: Alpadi K
PROVIDER: S-EPMC3258921 | biostudies-literature | 2008 Sep
REPOSITORIES: biostudies-literature
Alpadi Kannan K Magupalli Venkat Giri VG Käppel Stefanie S Köblitz Louise L Schwarz Karin K Seigel Gail M GM Sung Ching-Hwa CH Schmitz Frank F
The Journal of biological chemistry 20080729 39
Munc119 (also denoted as RG4) is a mammalian ortholog of the Caenorhabditis elegans protein unc119 and is essential for vision and synaptic transmission at photoreceptor ribbon synapses by unknown molecular mechanisms. Munc119/RG4 is related to the prenyl-binding protein PrBP/delta and expressed at high levels in photoreceptor ribbon synapses. Synaptic ribbons are presynaptic specializations in the active zone of these tonically active synapses and contain RIBEYE as a unique and major component. ...[more]