Ontology highlight
ABSTRACT:
SUBMITTER: Kilpelainen TO
PROVIDER: S-EPMC3262230 | biostudies-literature | 2011 Jun
REPOSITORIES: biostudies-literature
Nature genetics 20110626 8
Genome-wide association studies have identified 32 loci influencing body mass index, but this measure does not distinguish lean from fat mass. To identify adiposity loci, we meta-analyzed associations between ∼2.5 million SNPs and body fat percentage from 36,626 individuals and followed up the 14 most significant (P < 10(-6)) independent loci in 39,576 individuals. We confirmed a previously established adiposity locus in FTO (P = 3 × 10(-26)) and identified two new loci associated with body fat ...[more]