Ontology highlight
ABSTRACT:
SUBMITTER: Lewis JE
PROVIDER: S-EPMC5484705 | biostudies-literature | 2017 Jun
REPOSITORIES: biostudies-literature
Lewis Jo E JE Samms Ricardo J RJ Cooper Scott S Luckett Jeni C JC Perkins Alan C AC Adams Andrew C AC Tsintzas Kostas K Ebling Francis J P FJP
Scientific reports 20170626 1
FGF21 exerts profound metabolic effects in Siberian hamsters exposed to long day (LD) photoperiods that increase appetite and adiposity, however these effects are attenuated in short day (SD) animals that display hypophagia and reduced adiposity. The aim of this study was to investigate whether the beneficial effects of a novel mimetic of FGF21 in the LD state are a consequence of increased adiposity or of the central photoperiodic state. This was achieved by investigating effects of FGF21 in ag ...[more]