Ontology highlight
ABSTRACT:
SUBMITTER: Sharma AK
PROVIDER: S-EPMC3262594 | biostudies-literature | 2012 Feb
REPOSITORIES: biostudies-literature
The FEBS journal 20111222 3
Enzymatic catalysis and protein signaling are dynamic processes that involve local and/or global conformational changes occurring across a broad range of time scales. (1) H-(15) N relaxation NMR provides a comprehensive understanding of protein backbone dynamics both in the apo (unliganded) and ligand-bound conformations, enabling both fast and slow internal motions of individual amino acid residues to be observed. We recently reported the structure and nucleotide binding properties of the sulfa ...[more]