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Possible laboratory contamination leads to incorrect reporting of Vibrio cholerae O1 and initiates an outbreak response.


ABSTRACT: Vibrio cholerae O1 in a river water specimen in South Africa was reported, and a public health response followed in order to prevent an outbreak. Further investigation determined this to be a pseudoalert of V. cholerae O1, possibly linked to laboratory contamination. Following culture of bacteria from the water specimen, the testing laboratory possibly contaminated the culture with a V. cholerae O1 reference strain and then mistakenly reported isolation of V. cholerae O1.

SUBMITTER: Smith AM 

PROVIDER: S-EPMC3264189 | biostudies-literature | 2012 Feb

REPOSITORIES: biostudies-literature

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Possible laboratory contamination leads to incorrect reporting of Vibrio cholerae O1 and initiates an outbreak response.

Smith Anthony M AM   Keddy Karen H KH   Ismail Husna H   Tau Nomsa N   Sooka Arvinda A   Archer Brett N BN   Thomas Juno J   Crisp Noreen N  

Journal of clinical microbiology 20111207 2


Vibrio cholerae O1 in a river water specimen in South Africa was reported, and a public health response followed in order to prevent an outbreak. Further investigation determined this to be a pseudoalert of V. cholerae O1, possibly linked to laboratory contamination. Following culture of bacteria from the water specimen, the testing laboratory possibly contaminated the culture with a V. cholerae O1 reference strain and then mistakenly reported isolation of V. cholerae O1. ...[more]

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