Ontology highlight
ABSTRACT:
SUBMITTER: Moss JA
PROVIDER: S-EPMC3264253 | biostudies-literature | 2012 Feb
REPOSITORIES: biostudies-literature
Moss John A JA Malone Amanda M AM Smith Thomas J TJ Kennedy Sean S Kopin Etana E Nguyen Cali C Gilman Josh J Butkyavichene Irina I Vincent Kathleen L KL Motamedi Massoud M Friend David R DR Clark Meredith R MR Baum Marc M MM
Antimicrobial agents and chemotherapy 20111128 2
Vaginal microbicides may play an important role in protecting women from HIV infection. A strong synergy between HSV and HIV has been observed, and epidemiological studies demonstrate that HSV infection increases the risk of HIV acquisition. Incorporation of the antiretroviral tenofovir (TFV) along with the antiherpetic acyclovir (ACV) into combination intravaginal rings (IVRs) for sustained mucosal delivery of both compounds could lead to increased microbicide product adherence and efficacy com ...[more]