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An information-carrying and knowledge-producing molecular machine. A Monte-Carlo simulation.


ABSTRACT: The concept called Knowledge is a measure of the quality of genetically transferred information. Its usefulness is demonstrated quantitatively in a Monte-Carlo simulation on critical steps in a origin of life model. The model describes the origin of a bio-like genetic apparatus by a long sequence of physical-chemical steps: it starts with the presence of a self-replicating oligomer and a specifically structured environment in time and space that allow for the formation of aggregates such as assembler-hairpins-devices and, at a later stage, an assembler-hairpins-enzyme device-a first translation machine.

SUBMITTER: Kuhn C 

PROVIDER: S-EPMC3267034 | biostudies-literature | 2012 Feb

REPOSITORIES: biostudies-literature

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An information-carrying and knowledge-producing molecular machine. A Monte-Carlo simulation.

Kuhn Christoph C  

Journal of molecular modeling 20110511 2


The concept called Knowledge is a measure of the quality of genetically transferred information. Its usefulness is demonstrated quantitatively in a Monte-Carlo simulation on critical steps in a origin of life model. The model describes the origin of a bio-like genetic apparatus by a long sequence of physical-chemical steps: it starts with the presence of a self-replicating oligomer and a specifically structured environment in time and space that allow for the formation of aggregates such as asse  ...[more]

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