Understanding the physiological roles of the neuronal calcium sensor proteins.
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ABSTRACT:
SUBMITTER: Burgoyne RD
PROVIDER: S-EPMC3271974 | biostudies-literature | 2012 Jan
REPOSITORIES: biostudies-literature
Publications
Understanding the physiological roles of the neuronal calcium sensor proteins.
Burgoyne Robert D RD Haynes Lee P LP
Molecular brain 20120123 1
Calcium signalling plays a crucial role in the control of neuronal function and plasticity. Changes in neuronal Ca2+ concentration are detected by Ca2+-binding proteins that can interact with and regulate target proteins to modify their function. Members of the neuronal calcium sensor (NCS) protein family have multiple non-redundant roles in the nervous system. Here we review recent advances in the understanding of the physiological roles of the NCS proteins and the molecular basis for their spe ...[more]
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