Ontology highlight
ABSTRACT:
SUBMITTER: Yang M
PROVIDER: S-EPMC3273814 | biostudies-literature | 2012 Feb
REPOSITORIES: biostudies-literature
Yang Min M Gao Chunhui C Cui Tao T An Jingning J He Zheng-Guo ZG
Nucleic acids research 20111005 3
Transcriptional regulation plays a critical role in the life cycle of Mycobacterium smegmatis and its related species, M. tuberculosis, the causative microbe for tuberculosis. However, the key transcriptional factors involved in broad regulation of diverse genes remain to be characterized in mycobacteria. In the present study, a TetR-like family transcriptional factor, Ms6564, was characterized in M. smegmatis as a master regulator. A conserved 19 bp-palindromic motif was identified for Ms6564 b ...[more]