Ontology highlight
ABSTRACT:
SUBMITTER: Mao R
PROVIDER: S-EPMC3278313 | biostudies-literature | 2012 Mar
REPOSITORIES: biostudies-literature
Mao Rong R Schummers James J Knoblich Ulf U Lacey Carolyn J CJ Van Wart Audra A Cobos Inma I Kim Carol C Huguenard John R JR Rubenstein John L R JL Sur Mriganka M
Cerebral cortex (New York, N.Y. : 1991) 20110610 3
Inhibition modulates receptive field properties and integrative responses of neurons in cortical circuits. The contribution of specific interneuron classes to cortical circuits and emergent responses is unknown. Here, we examined neuronal responses in primary visual cortex (V1) of adult Dlx1(-/-) mice, which have a selective reduction in cortical dendrite-targeting interneurons (DTIs) that express calretinin, neuropeptide Y, and somatostatin. The V1 neurons examined in Dlx1(-/-) mice have reduce ...[more]