Ontology highlight
ABSTRACT:
SUBMITTER: Khan AG
PROVIDER: S-EPMC6390950 | biostudies-literature | 2018 Jun
REPOSITORIES: biostudies-literature
Khan Adil G AG Poort Jasper J Chadwick Angus A Blot Antonin A Sahani Maneesh M Mrsic-Flogel Thomas D TD Hofer Sonja B SB
Nature neuroscience 20180521 6
How learning enhances neural representations for behaviorally relevant stimuli via activity changes of cortical cell types remains unclear. We simultaneously imaged responses of pyramidal cells (PYR) along with parvalbumin (PV), somatostatin (SOM), and vasoactive intestinal peptide (VIP) inhibitory interneurons in primary visual cortex while mice learned to discriminate visual patterns. Learning increased selectivity for task-relevant stimuli of PYR, PV and SOM subsets but not VIP cells. Strikin ...[more]