Ontology highlight
ABSTRACT:
SUBMITTER: Xiong X
PROVIDER: S-EPMC3280217 | biostudies-literature | 2012 Jan
REPOSITORIES: biostudies-literature
Xiong Xin X Collins Catherine A CA
The Journal of neuroscience : the official journal of the Society for Neuroscience 20120101 2
Axons are vulnerable components of neuronal circuitry, and neurons are equipped with mechanisms for responding to axonal injury. A highly studied example of this is the conditioning lesion, in which neurons that have been previously injured have an increased ability to initiate new axonal growth (Hoffman, 2010). Here we investigate the effect of a conditioning lesion on axonal degeneration, which occurs in the distal stump after injury, and also occurs in neuropathies and neurodegenerative disor ...[more]