TIM polymorphisms--genetics and function.
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ABSTRACT:
SUBMITTER: Lee J
PROVIDER: S-EPMC3281969 | biostudies-literature | 2011 Dec
REPOSITORIES: biostudies-literature
Publications
TIM polymorphisms--genetics and function.
Lee J J Phong B B Egloff A M AM Kane L P LP
Genes and immunity 20111103 8
The transmembrane immunoglobulin and mucin domain (TIM) family was identified more than a decade ago. Although the founding member of the family was first described in a rat model of ischemia-reperfusion injury, much of the recent interest in the TIM family members has focused on their potential roles in immunity. There are now a large number of genetic studies that have investigated the possible association of various TIM1 and TIM3 polymorphisms with different diseases. Here, we review this bod ...[more]
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