Ontology highlight
ABSTRACT:
SUBMITTER: Yang X
PROVIDER: S-EPMC3287024 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Yang Xiaodong X Balakrishnan Ilango I Torok-Storb Beverly B Pillai Manoj M MM
Advances in hematology 20120216
Marrow stromal cells (MSCs, also termed mesenchymal stem cells) have been proposed as a promising cellular therapy for tissue injury including radiation-induced marrow failure, but evidence for a direct effect is lacking. To assess the effects of MSCs on survival after lethal irradiation, we infused syngeneic MSCs (either as immortalized MSCs clones or primary MSCs) intravenously into wild-type C57/Bl6 mice within 24 hours of lethal total body irradiation (TBI). Mice receiving either of the MSC ...[more]