Unknown

Dataset Information

0

Discovery and genomic characterization of noroviruses from a gastroenteritis outbreak in domestic cats in the US.


ABSTRACT: Norovirus (NoV) RNA was detected in the stools of 6 out 14 (42.8%) 8-12-week-old cats with enteritis from a feline shelter, in New York State. Upon sequence analysis of the complete capsid, the six NoVs were found to be identical, suggesting the spread of a unique NoV strain in the shelter. The full-length genomic sequence (7839 nt) of one feline NoV, CU081210E/2010/US, was determined. In the capsid protein VP1 region, the virus displayed the highest amino acid identity to animal genogroup IV genotype 2 (GIV.2) NoVs: lion/Pistoia-387/06/IT (97.9%) and dog/Bari-170/07/IT (90.4%). These findings document the discovery of a novel feline calicivirus, different from vesiviruses, and extend the spectrum of NoV host range. Epidemiological studies using feline NoV-specific diagnostic tools and experimental infection of cats are required to understand whether NoVs have a pathogenic role in this species.

SUBMITTER: Pinto P 

PROVIDER: S-EPMC3289677 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature

altmetric image

Publications

Discovery and genomic characterization of noroviruses from a gastroenteritis outbreak in domestic cats in the US.

Pinto Pierfrancesco P   Wang Qiuhong Q   Chen Ning N   Dubovi Edward J EJ   Daniels Joshua B JB   Millward Laurie M LM   Buonavoglia Canio C   Martella Vito V   Saif Linda J LJ  

PloS one 20120228 2


Norovirus (NoV) RNA was detected in the stools of 6 out 14 (42.8%) 8-12-week-old cats with enteritis from a feline shelter, in New York State. Upon sequence analysis of the complete capsid, the six NoVs were found to be identical, suggesting the spread of a unique NoV strain in the shelter. The full-length genomic sequence (7839 nt) of one feline NoV, CU081210E/2010/US, was determined. In the capsid protein VP1 region, the virus displayed the highest amino acid identity to animal genogroup IV ge  ...[more]

Similar Datasets

| S-EPMC1393082 | biostudies-literature
| S-EPMC3166754 | biostudies-literature
| S-EPMC3147480 | biostudies-literature
| S-EPMC3165588 | biostudies-literature
| S-EPMC404621 | biostudies-literature
| S-EPMC5925730 | biostudies-literature
| S-EPMC6746754 | biostudies-literature
| S-EPMC7118673 | biostudies-literature
| S-EPMC6177177 | biostudies-literature
| S-EPMC7200058 | biostudies-literature