Single-walled carbon nanotube-based chemiresistive affinity biosensors for small molecules: ultrasensitive glucose detection.
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ABSTRACT:
SUBMITTER: Cella LN
PROVIDER: S-EPMC3292278 | biostudies-literature | 2010 Apr
REPOSITORIES: biostudies-literature
Publications
Single-walled carbon nanotube-based chemiresistive affinity biosensors for small molecules: ultrasensitive glucose detection.
Cella Lakshmi N LN Chen Wilfred W Myung Nosang V NV Mulchandani Ashok A
Journal of the American Chemical Society 20100401 14
We report for the first time single-walled carbon nanotube (SWNT)-based chemiresistive affinity sensors for highly sensitive and selective detection of small and/or weakly charged or uncharged molecules using a displacement format. The detection of glucose, a small, weakly charged molecule, by displacement of plant lectin (concavalin A) bound to a polysaccharide (dextran) immobilized on SWNTs with picomolar sensitivity and selectivity over other sugars and human serum proteins is demonstrated as ...[more]
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