Ontology highlight
ABSTRACT:
SUBMITTER: Wick G
PROVIDER: S-EPMC3292797 | biostudies-literature | 2006
REPOSITORIES: biostudies-literature
Wick Georg G Andersson Leif L Hala Karel K Gershwin M Eric ME Selmi Carlo C Erf Gisela F GF Lamont Susan J SJ Sgonc Roswitha R
Advances in immunology 20060101
Autoimmune diseases in human patients only become clinically manifest when the disease process has developed to a stage where functional compensation by the afflicted organ or system is not possible anymore. In order to understand the initial etiologic and pathogenic events that are generally not yet accessible in humans, appropriate animal models are required. In this respect, spontaneously developing models--albeit rare--reflect the situation in humans much more closely than experimentally ind ...[more]