Ontology highlight
ABSTRACT:
SUBMITTER: Yamasaki K
PROVIDER: S-EPMC3293589 | biostudies-literature | 2012 Mar
REPOSITORIES: biostudies-literature
Yamasaki Kazuhiko K Kigawa Takanori T Watanabe Satoru S Inoue Makoto M Yamasaki Tomoko T Seki Motoaki M Shinozaki Kazuo K Yokoyama Shigeyuki S
The Journal of biological chemistry 20120104 10
The WRKY family transcription factors regulate plant-specific reactions that are mostly related to biotic and abiotic stresses. They share the WRKY domain, which recognizes a DNA element (TTGAC(C/T)) termed the W-box, in target genes. Here, we determined the solution structure of the C-terminal WRKY domain of Arabidopsis WRKY4 in complex with the W-box DNA by NMR. A four-stranded β-sheet enters the major groove of DNA in an atypical mode termed the β-wedge, where the sheet is nearly perpendicula ...[more]