Ribulokinase and transcriptional regulation of arabinose metabolism in Clostridium acetobutylicum.
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ABSTRACT:
SUBMITTER: Zhang L
PROVIDER: S-EPMC3294803 | biostudies-literature | 2012 Mar
REPOSITORIES: biostudies-literature
Publications
Ribulokinase and transcriptional regulation of arabinose metabolism in Clostridium acetobutylicum.
Zhang Lei L Leyn Semen A SA Gu Yang Y Jiang Weihong W Rodionov Dmitry A DA Yang Chen C
Journal of bacteriology 20111222 5
The transcription factor AraR controls utilization of L-arabinose in Bacillus subtilis. In this study, we combined a comparative genomic reconstruction of AraR regulons in nine Clostridium species with detailed experimental characterization of AraR-mediated regulation in Clostridium acetobutylicum. Based on the reconstructed AraR regulons, a novel ribulokinase, AraK, present in all analyzed Clostridium species was identified, which was a nonorthologous replacement of previously characterized rib ...[more]
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