Ontology highlight
ABSTRACT:
SUBMITTER: Paredes CJ
PROVIDER: S-EPMC390361 | biostudies-literature | 2004
REPOSITORIES: biostudies-literature
Paredes Carlos J CJ Rigoutsos Isidore I Papoutsakis E Terry ET
Nucleic acids research 20040401 6
Prokaryotic genes are frequently organized in multicistronic operons (or transcriptional units, TUs), and usually the regulatory motifs for the whole TU are located upstream of the first TU gene. Although the number of sequenced genomes has increased dramatically, experimental information on TU organization is extremely limited. Even for organisms as extensively studied as Escherichia coli and Bacillus subtilis, TU annotation is far from complete. It therefore becomes imperative to rely on compu ...[more]