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Molecular characterization of Escherichia coli strains that cause symptomatic and asymptomatic urinary tract infections.


ABSTRACT: The differences between Escherichia coli strains associated with symptomatic and asymptomatic urinary tract infections (UTIs) remain to be properly determined. Here we examined the prevalence of plasmid types and bacteriocins, as well as genetic relatedness, in a defined collection of E. coli strains that cause UTIs. Comparative analysis identified a subgroup of strains with a high number of virulence genes (VGs) and microcins M/H47. We also identified associations between microcin genes, VGs, and specific plasmid types.

SUBMITTER: Abraham S 

PROVIDER: S-EPMC3295173 | biostudies-literature | 2012 Mar

REPOSITORIES: biostudies-literature

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Molecular characterization of Escherichia coli strains that cause symptomatic and asymptomatic urinary tract infections.

Abraham Sam S   Chapman Toni A TA   Zhang Ren R   Chin James J   Mabbett Amanda N AN   Totsika Makrina M   Schembri Mark A MA  

Journal of clinical microbiology 20111221 3


The differences between Escherichia coli strains associated with symptomatic and asymptomatic urinary tract infections (UTIs) remain to be properly determined. Here we examined the prevalence of plasmid types and bacteriocins, as well as genetic relatedness, in a defined collection of E. coli strains that cause UTIs. Comparative analysis identified a subgroup of strains with a high number of virulence genes (VGs) and microcins M/H47. We also identified associations between microcin genes, VGs, a  ...[more]

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